Why does Peter McCullough say spike protein can persist years after an mRNA vaccine?

Peter McCullough told Joe Rogan that natural messenger RNA is broken down after one use, but the Pfizer and Moderna shots replaced every uracil with pseudouridine, which he says makes the molecule almost resistant to breakdown. He described a patient of his whose blood, tested at a German lab, still showed vaccine material and spike protein three and a half years after the shot. He believes people with weaker clearance enzymes are the ones who accumulate it.

• McCullough said the patient developed blood clots and MRI-proven myocarditis after two Pfizer doses and more clots after a booster.
• McCullough said antibodies normally neutralise the spike, but a switch to the IgG4 subclass can leave it unopposed and damage the heart.
• McCullough recommends nattokinase, bromelain and curcumin to clear spike protein, a formula sold by the Wellness Company as Ultimate Spike Detox.

Source: our own transcription of the episode. The full conversation is on The Joe Rogan Experience (2026-11-04). Read the whole episode summary →

▸More from this episode